Responses of TCR Transduced T Cells Requirements for Effective Antitumor
نویسندگان
چکیده
منابع مشابه
Requirements for effective antitumor responses of TCR transduced T cells.
Adoptive transfer of TCR gene-modified T cells has been proposed as an attractive approach to target tumors for which it is difficult or impossible to induce strong tumor-specific T cell responses by vaccination. Whereas the feasibility of generating tumor Ag-specific T cells by gene transfer has been demonstrated, the factors that determine the in vivo effectiveness of TCR-modified T cells are...
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